CD44 Antikörper

Produktnummer ABIN1177309

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD44 in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für CD44 Antikörper (ABIN1177309)

Target: CD44

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 515

Produktdetails anti-CD44 Antikörper

Marke: BD Pharmingen™

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Referenzen für anti-CD44 Antikörper (ABIN1177309)

Kansas, Muirhead, Dailey: "Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans." in: Blood, Vol. 76, Issue 12, pp. 2483-92, (1991) (PubMed).

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44 (Pgp-1, H-CAM, Ly24)

Hintergrund: Reacts with CD44, and 85 kDa glycoprotein that is expressed on leukocytes, erythrocytes, epithelial cells and weakly on platelets. CD44 is a member of the hyaladherin family of hyaluronan-binding proteins, with structural similarities to selectins. It has a functional role in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation. 515 monoclonal antibody has been reported to be able to block cell adhesion to the hyaluronic acid. Flow cytometric analysis for CD44. Human peripheral blood lymphocytes were stained either with the Purified NA/LE Mouse Anti-Human CD44 antibody (solid line) or a Mouse IgG1 isotype control (dashed line) followed by a FITC Goat Anti-Mouse IgG/IgM polyclonal secondary antibody and analyzed on a BD FACScan™ instrument.
Synonyms: Pgp-1, H-CAM, Ly24

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling